Plykine

Plykine is a quick, often-fatal disease that comes in fast, deadly bursts. Those effected by the disease feel their limbs stiffen and paralyze, leaving the flesh brittle and cracking. The disease has no non-magical cure known, but it can occasionally kill itself in its victim, letting the host survive. However, survivors are not immune to catching the plague again. Those who posses the disease or survive it are often called "glass-fingered" as many of their digits or limbs are immobile and prone to shattering like glass.

Plykine only takes around two days to completely kill a target. Those who share fluid contact with a victim is prone to receiving the disease themselves, and suffering just the same.